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Keywords:

  • Down syndrome;
  • screening;
  • nuchal translucency;
  • ultrasound

Abstract

Objectives

To assess the effect of altering image size on the absolute nuchal translucency (NT) measurement.

Methods

NT was measured at three image magnifications (60%, 100% and 200%) in 120 singleton pregnancies.

Results

The mean ± SD NT measurements were 1.52 ± 0.57 mm, 1.35 ± 0.53 mm and 1.18 ± 0.48 mm at 60%, 100% and 200% magnification, respectively (p = 0.00001).

Conclusions

The measurement of NT decreases significantly with increasing image size. Optimisation of NT as a method of screening will require agreed standardisation of image magnification. Copyright © 2003 John Wiley & Sons, Ltd.