Retracted: Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery


  • Frank Krummenauer,

    Corresponding author
    1. Clinical Epidemiology and Health Economy Unit Dresden University of Technology, Germany
    • Clinical Epidemiology and Health Economy Unit, University Hospital Carl Gustav Carus Dresden, Medical Faculty of Dresden University of Technology; Fetscherstrße 74 (bd 29), D-03107 Dresden (Germany).
    Search for more papers by this author
    • Proprietary Interest Statement: None of the authors has a commercial or financial interest whatsoever in any point mentioned in the paper.

  • Sabine Kurz,

    1. University Eye Hospital, University of Mainz, Germany
    Search for more papers by this author
  • H. Burkhard Dick

    1. University Eye Hospital, University of Bochum, Germany
    Search for more papers by this author


This article is corrected by:

  1. Errata: Retraction Volume 22, Issue 2, 221, Article first published online: 5 February 2013

  • No conflict of interest was declared.

  • Congress Presentations: At the 47th meeting of the German Society for Medical Biometry, Epidemiology and Informatics GMDS, Berlin, Germany, September 2002.



To evaluate risk factors for endophthalmitis after cataract surgery and to retest recent findings on the protective effect of intraoperative antibiosis and the promoting effect of the clear corneal as compared to sclerocorneal incision.


Survey study.


Five hundred thirty-eight ophthalmosurgical centers in Germany.

Main Outcome Measure

Responder specific endophthalmitis incidence.


A total of 310 (58%) questionnaires were computed resulting in an overall count of 404 356 cataract surgeries and 291 self-reported endophthalmitis cases (crude rate 0.072%). The risk of postoperative endophthalmitis for sclerocorneal versus clear corneal incisions was not significantly reduced (relative risk 0.97, 99% confidence interval 0.69–1.38). The hypothesis of a protective effect of intraocular antibiosis could be confirmed by a significantly decreased risk ratio of 0.69 (99% confidence interval 0.48–0.99) indicating a significant benefit from intraoperative intraocular antibiosis. A similar tendency was observed for an intraoperative periocular antibiosis with a significantly reduced risk ratio of 0.68 (99% confidence interval 0.49–0.96). These risk estimates had been adjusted for the size of the surgical center: a significantly reduced risk ratio of 0.70 (99% confidence interval 0.49–0.98) for postoperative endophthalmitis was observed for local centers.


Whereas this 2001 appraisal of a survey in 1996 could not reproduce the benefit of sclerocorneal incision, the protective effect of intraoperative intraocular antibiotic prophylaxis could be confirmed. However, the results of this survey have to be interpreted with care, since it is not based on individual case information, but rather on aggregate questionnaire data. Copyright © 2006 John Wiley & Sons, Ltd.