No conflict of interest was declared.
Complete blindness after optic neuropathy induced by short-term linezolid treatment in a patient suffering from muscle dystrophy†
Article first published online: 25 SEP 2006
Copyright © 2006 John Wiley & Sons, Ltd.
Pharmacoepidemiology and Drug Safety
Volume 16, Issue 4, pages 402–404, April 2007
How to Cite
Azamfirei, L., Copotoiu, S.-M., Branzaniuc, K., Szederjesi, J., Copotoiu, R. and Berteanu, C. (2007), Complete blindness after optic neuropathy induced by short-term linezolid treatment in a patient suffering from muscle dystrophy. Pharmacoepidem. Drug Safe., 16: 402–404. doi: 10.1002/pds.1320
- Issue published online: 22 MAR 2007
- Article first published online: 25 SEP 2006
- Manuscript Accepted: 5 AUG 2006
- Manuscript Revised: 15 MAY 2006
- Manuscript Received: 25 APR 2006
- muscle dystrophy
We present a case of severe optic neuropathy following linezolid treatment, which led to complete irreversible blindness, in a patient with progressive muscular dystrophy, treated with linezolid for 16 days for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. Interruption of antibiotic therapy did not lead to remission of ocular symptoms. Administration of linezolid may lead to severe neuropathy even in the case of short-term treatment. Copyright © 2006 John Wiley & Sons, Ltd.