No conflict of interest was declared.
Agreement between administrative databases and medical charts for pregnancy-related variables among asthmatic women†
Article first published online: 13 FEB 2008
Copyright © 2008 John Wiley & Sons, Ltd.
Pharmacoepidemiology and Drug Safety
Volume 17, Issue 4, pages 345–353, April 2008
How to Cite
Vilain, A., Otis, S., Forget, A. and Blais, L. (2008), Agreement between administrative databases and medical charts for pregnancy-related variables among asthmatic women. Pharmacoepidem. Drug Safe., 17: 345–353. doi: 10.1002/pds.1558
- Issue published online: 26 MAR 2008
- Article first published online: 13 FEB 2008
- Manuscript Accepted: 4 JAN 2008
- Manuscript Revised: 4 DEC 2007
- Manuscript Received: 17 JUL 2007
- pregnancy-related variables;
- administrative databases;
- medical chart;
To determine the validity of pregnancy variables recorded in administrative databases of Quebec using patient medical charts as the gold standard among asthmatic pregnant women.
Three administrative databases were linked and provided information on maternal, pregnancy and infant characteristics for 726 pregnant asthmatic women who delivered in 1990–2000. Algorithms were developed to measure variables that were not recorded directly in the databases or to minimize the number of missing values for variables recorded in two or more databases. Medical file data were collected by two trained research nurses in 43 hospitals. The validity of categorical variables was assessed with sensitivity, specificity, predictive positive values (PPVs) and predictive negative values (PNVs), whereas the validity of continuous variables was assessed with Pearson correlation using the medical chart as the gold standard.
The sensitivity of the sex of the baby, previous live birth and previous pregnancy ranged from 0.97 to 0.99. Corresponding figures were 0.92–0.98 for specificity. We also found high correlation coefficients, ranging from 0.875 to 0.999 for the length of gestation, dates of last menstruation and delivery, maternal age and birth weight.
Pregnancy-related variables recorded in administrative databases or derived from algorithms based on two or more databases were found to be highly valid as compared to the medical chart among asthmatic women. Copyright © 2008 John Wiley & Sons, Ltd.