This document has been endorsed by the International Society for Pharmacoepidemiology as policy and has been posted on their website as a preprint version.
Guidelines for good database selection and use in pharmacoepidemiology research†
Article first published online: 8 NOV 2011
Copyright © 2011 John Wiley & Sons, Ltd.
Pharmacoepidemiology and Drug Safety
Volume 21, Issue 1, pages 1–10, January 2012
How to Cite
Hall, G. C., Sauer, B., Bourke, A., Brown, J. S., Reynolds, M. W. and Casale, R. L. (2012), Guidelines for good database selection and use in pharmacoepidemiology research. Pharmacoepidem. Drug Safe., 21: 1–10. doi: 10.1002/pds.2229
- Issue published online: 4 JAN 2012
- Article first published online: 8 NOV 2011
- Manuscript Accepted: 19 JUL 2011
- Manuscript Revised: 4 JUL 2011
- Manuscript Received: 8 MAR 2011
- Health databases;
- research design;
The use of healthcare databases in research provides advantages such as increased speed, lower costs and limitation of some biases. However, database research has its own challenges as studies must be performed within the limitations of resources, which often are the product of complex healthcare systems. The primary purpose of this document is to assist in the selection and use of data resources in pharmacoepidemiology, highlighting potential limitations and recommending tested procedures. This guidance is presented as a detailed text with a checklist for quick reference and covers six areas: selection of a database, use of multiple data resources, extraction and analysis of the study population, privacy and security, quality and validation procedures and documentation. Copyright © 2011 John Wiley & Sons, Ltd.