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Additional supporting information may be found in the online version of this article.

e-Table 1: First three higher prevalence diagnoses in PIM recipients compared to sex and aged matched controls, accounted for in sensitivity analysis.

e-Table 2: Annual treatment prevalence of the insured population (≥ 0,1%) and of PIM recipients (2010).

e-Table 3: Association of prevalent PIM prescription and risk factors adjusting for indications.

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