This research was conducted in the Child and Family Research Institute.
High use of health services in patients with suboptimal asthma drug regimens: a population-based assessment in British Columbia, Canada†
Article first published online: 5 APR 2013
Copyright © 2013 John Wiley & Sons, Ltd.
Pharmacoepidemiology and Drug Safety
Volume 22, Issue 7, pages 744–751, July 2013
How to Cite
Zhang, T., Smith, M. A., Camp, P. G. and Carleton, B. C. (2013), High use of health services in patients with suboptimal asthma drug regimens: a population-based assessment in British Columbia, Canada. Pharmacoepidem. Drug Safe., 22: 744–751. doi: 10.1002/pds.3444
Ethical approval for this study was obtained from the University of British Columbia's Behavioural Research Ethics Board.
- Issue published online: 3 JUL 2013
- Article first published online: 5 APR 2013
- Manuscript Accepted: 6 MAR 2013
- Manuscript Revised: 15 FEB 2013
- Manuscript Received: 13 JUN 2012
- Canadian Institutes of Health Research (CIHR)
- CIHR Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT)
- suboptimal drug regimens;
- health service utilization;
Despite numerous clinical guidelines on asthma management, patients often receive suboptimal drug therapy. This study identified patients who received suboptimal regimens according to the National Heart, Lung and Blood Institute (NHLBI) Guidelines for the Diagnosis and Management of Asthma in a complete population (residents of British Columbia, Canada) and determined the association between patients' regimens and utilization of healthcare services.
A total of 65 345 asthma patients were identified using provincial health service utilization data (including all respiratory-related prescription medication dispensings, physician and hospital visits) for the 2009 fiscal year. Patient-specific regimens of inhaled short-acting bronchodilators (SABA) with or without inhaled corticosteroids (ICS) were categorized as optimal or suboptimal. Logistic regression models were used to determine the association between regimen optimality and health service utilization, adjusted for socioeconomic status, prior year hospital and emergency department (ED) visits for asthma.
Patients with suboptimal regimens had significantly greater risk of using health services than patients with optimal regimens of SABA and/or ICS. In particular, adolescents with suboptimal regimens were the most likely to have hospital admissions (odds ratio (OR) 3.8; 95% confidence interval (CI) 1.8–7.8), visit the ED (OR 2.2; 95% CI 1.6–3.1) and be high users of family physician services (OR 5.7; 95% CI 4.0–8.1) compared with patients in other age groups.
Suboptimal regimens are associated with significantly high usage of health services. Identifying patients with suboptimal regimens and improving their medication management in accordance with asthma clinical guidelines are likely to result in lower health service utilization. Copyright © 2013 John Wiley & Sons, Ltd.