Much ado about something: The weight of evidence for PCB effects on neuropsychological function
Version of Record online: 15 JUN 2004
Copyright © 2004 Wiley Periodicals, Inc.
Psychology in the Schools
Special Issue: PCBs and Developmental Outcomes: A Critical Debate
Volume 41, Issue 6, pages 669–679, July 2004
How to Cite
Schantz, S. L., Gardiner, J. C., Gasior, D. M., McCaffrey, R. J., Sweeney, A. M. and Humphrey, H. E.B. (2004), Much ado about something: The weight of evidence for PCB effects on neuropsychological function. Psychol. Schs., 41: 669–679. doi: 10.1002/pits.20008
- Issue online: 15 JUN 2004
- Version of Record online: 15 JUN 2004
D.V. Cicchetti, A.S. Kaufman, and S.S. Sparrow (this issue) use six criteria to evaluate the published findings from seven different studies of PCB exposure and neuropsychological function. They point out a number of weaknesses or flaws in each study and conclude that these weaknesses make the overall conclusion that PCB exposure negatively impacts neuropsychological function untenable. While we agree that all of the studies have weaknesses, we take issue with some of the specific criticisms Cicchetti and colleagues make including their comments on exposure assessment, statistical control of multiple comparisons, validity of test instruments and clinical relevance of the findings. We argue that—despite the weaknesses of each individual study—the consistency of effects across studies is remarkable, and we conclude that the weight of evidence for a negative association between PCB exposure and intellectual function in childhood is very strong. © 2004 Wiley Periodicals, Inc. Psychol Schs 41: 669–679, 2004.