Technical Brief

GARBAN II: An integrative framework for extracting biological information from proteomic and genomic data

  1. Victoriano Segura1,
  2. Adam Podhorski1,
  3. Elizabeth Guruceaga1,
  4. José L. Sevilla2,
  5. Fernando J. Corrales3,
  6. Angel Rubio Dr.1,*

Article first published online: 18 APR 2006

DOI: 10.1002/pmic.200500313

Issue

PROTEOMICS

PROTEOMICS

Supplement: PROTEOMICS IN SPAIN Proceedings of the 1st Congress of the Spanish Proteomics Society Cordoba, Spain, 14–17 February 2005

Volume 6, Issue Supplement 1, pages S12–S15, No. S 1 April 2006

Additional Information

How to Cite

Segura, V., Podhorski, A., Guruceaga, E., Sevilla, J. L., Corrales, F. J. and Rubio, A. (2006), GARBAN II: An integrative framework for extracting biological information from proteomic and genomic data. Proteomics, 6: S12–S15. doi: 10.1002/pmic.200500313

Author Information

  1. 1

    Centro de Estudios e Investigaciones Técnicas de Guipúzcoa (CEIT) and Escuela Superior de Ingenieros de la Universidad de Navarra (TECNUN), San Sebastián, Spain

  2. 2

    Strathmore University, Nairobi, Kenya

  3. 3

    Centro de Investigación Médica Aplicada (CIMA), Pamplona, Spain

*CEIT, Paseo Manuel de Lardizabal, 15 San Sebastián 20018, Spain Fax: +34-943213076

Publication History

  1. Issue published online: 18 APR 2006
  2. Article first published online: 18 APR 2006
  3. Manuscript Received: 11 MAY 2005

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Keywords:

  • Bioinformatics;
  • Expression analysis;
  • Functional genomics;
  • Functional proteomics

Abstract

Genomic and proteomic analyses generate a massive amount of data that requires specific bioinformatic tools for its management and interpretation. GARBAN II, developed from the previous GARBAN platform, provides an integrated framework to simultaneously analyse and compare multiple datasets from DNA microarrays and proteomic studies. The general architecture, gene classification and comparison, and graphical representation have been redesigned to ensure a user-friendly feature and to improve the capabilities and efficiency of this system. Additionally, GARBAN II has been extended with new applications to display networks of coexpressed genes and to integrate access to BioRag and MotifScanner so as to facilitate the holistic analysis of users' data.

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