Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds

Authors

  • David J. Harvey,

    Corresponding author
    1. Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK
    • Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK. Fax: +44-1-1865-275216
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  • Anthony H. Merry,

    1. Glycosciences Consultancy, Charlbury, OXON, UK
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  • Louise Royle,

    1. Dublin-Oxford Glycobiology Laboratory, National Institute for Bioprocessing, Research and Training (NIBRT), Conway Institute, University College Dublin, Dublin, Ireland
    Current affiliation:
    1. Ludger Ltd., Culham Science Centre, Oxfordshire, OX14 3EB, UK
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  • Matthew P. Campbell,

    1. Dublin-Oxford Glycobiology Laboratory, National Institute for Bioprocessing, Research and Training (NIBRT), Conway Institute, University College Dublin, Dublin, Ireland
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  • Raymond A. Dwek,

    1. Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK
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  • Pauline M. Rudd

    1. Dublin-Oxford Glycobiology Laboratory, National Institute for Bioprocessing, Research and Training (NIBRT), Conway Institute, University College Dublin, Dublin, Ireland
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Errata

This article is corrected by:

  1. Errata: Erratum: Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds Volume 9, Issue 21, 5002, Article first published online: 27 October 2009

Abstract

Symbolic diagrams are commonly used to depict N- and O-linked glycans but there is no general consensus as to how individual constituent monosaccharides or linkages are shown. This article proposes a system that avoids ambiguities inherent in most other systems and is appropriate for both hand drawing and computer applications. Constituent monosaccharides are depicted by shapes modified to show OAc, deoxy, etc. Linkage is indicated by the bond angle and anomericity by solid (β) or dashed (α) lines.

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