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Proteome profile of whole cerebellum of the mature rat

Authors

  • Devendra Kumar Maurya,

    1. Centre for Cellular & Molecular Biology, (Council of Scientific and Industrial Research), Hyderabad, India
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  • Curam Sreenivasacharlu Sundaram,

    1. Centre for Cellular & Molecular Biology, (Council of Scientific and Industrial Research), Hyderabad, India
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  • Purnima Bhargava

    Corresponding author
    1. Centre for Cellular & Molecular Biology, (Council of Scientific and Industrial Research), Hyderabad, India
    • Centre for Cellular & Molecular Biology, (Council of Scientific and Industrial Research), Uppal Road, Hyderabad 500007, India Fax: +91-40-27160591
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Abstract

Cerebellum is an important brain region involved in motor, cognition, learning and memory functions. Proteome mapping of the 21 days old rat cerebellum identified total 285 proteins, out of which 76 proteins were not reported earlier from rat brain. This includes 49 neuronal activity-specific proteins, 7 of which are reported for the first time from the cerebellum in this study. The protein sequence data for 31 proteins reported here have been integrated in the UniProt Knowledgebase.

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