These authors contributed equally to this work.
Sigpep: Calculating unique peptide signature transition sets in a complete proteome background
Article first published online: 11 MAY 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 12, Issue 8, pages 1142–1146, April 2012
How to Cite
Helsens, K., Mueller, M., Hulstaert, N. and Martens, L. (2012), Sigpep: Calculating unique peptide signature transition sets in a complete proteome background. Proteomics, 12: 1142–1146. doi: 10.1002/pmic.201100566
- Issue published online: 11 MAY 2012
- Article first published online: 11 MAY 2012
- Manuscript Accepted: 1 JAN 2012
- Manuscript Revised: 9 DEC 2011
- Manuscript Received: 28 OCT 2011
- Mass spectrometry;
- Selected reaction monitoring;
We have created a new software platform called sigpep that analyzes transition redundancy in selected reaction monitoring assays. Building on this platform, we also created a web application to generate transition sets with unique signatures for targeted peptides. The platform has been made available under the permissive Apache 2.0 open-source license, and the web application can be accessed from http://iomics.ugent.be/sigpep.