These authors contributed equally to this review.
Polymeric monolithic materials modified with nanoparticles for separation and detection of biomolecules: A review
Article first published online: 29 AUG 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Special Issue: Focus on Emerging Gel-Free Separation and Detection Methods
Volume 12, Issue 19-20, pages 2904–2917, October 2012
How to Cite
Connolly, D., Currivan, S. and Paull, B. (2012), Polymeric monolithic materials modified with nanoparticles for separation and detection of biomolecules: A review. Proteomics, 12: 2904–2917. doi: 10.1002/pmic.201200142
- Issue published online: 19 OCT 2012
- Article first published online: 29 AUG 2012
- Accepted manuscript online: 7 AUG 2012 08:44AM EST
- Manuscript Accepted: 10 MAY 2012
- Manuscript Revised: 1 MAY 2012
- Manuscript Received: 4 APR 2012
- Polymer monoliths;
Polymer monolithic materials have found particularly utility in the field of bioanalysis, particularly in the area of separation science, for both enrichment and trapping of biomolecules and their analytical/preparative separations. Nanoparticle-modified monoliths have recently emerged as a new class of substrate, with unique characteristics and structure, and with selectively tailored surface chemistries for target molecules. Although several reviews exist on the applications of nanoparticles in analytical science, this review is the first to specifically summarise the applications in bioanalysis of nanoparticle-modified polymer monolithic materials. The review covers the range of nanoparticles being utilised in this way, their specific applications and future trends.