These authors contributed equally to this work.
Proteomics analysis of human pericardial fluid
Article first published online: 5 AUG 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 13, Issue 17, pages 2692–2695, September 2013
How to Cite
Xiang, F., Guo, X., Chen, W., Wang, J., Zhou, T., Huang, F., Cao, C. and Chen, X. (2013), Proteomics analysis of human pericardial fluid. Proteomics, 13: 2692–2695. doi: 10.1002/pmic.201200317
- Issue published online: 2 SEP 2013
- Article first published online: 5 AUG 2013
- Accepted manuscript online: 25 JUN 2013 04:52AM EST
- Manuscript Accepted: 3 JUN 2013
- Manuscript Revised: 18 MAY 2013
- Manuscript Received: 24 JUL 2012
- Pericardial fluid;
- Systems biology
Pericardial fluid (PF) is considered as a biochemical window of heart. To date, there have been limited attempts to perform an in-depth analysis of the PF proteome. In this study, an SDS-PAGE-LC-MS/MS platform was utilized to explore depleted PF, which showed great coverage of low-abundant proteins. In total, 1007 nonredundant proteins were identified with at least two peptides. This is the first comprehensive analysis of human PF proteome and provides a foundation for further application of PF in cardiovascular research. The data have been deposited to the ProteomeXchange with identifier PXD000194.