These authors contributed equally to this work.
Phosphoproteome analysis of an early onset mouse model (TgCRND8) of Alzheimer's disease reveals temporal changes in neuronal and glia signaling pathways
Version of Record online: 2 APR 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Special Issue: FOCUS ON INTEGRATIVE PROTEOMICS
Volume 13, Issue 8, pages 1292–1305, April 2013
How to Cite
Wang, F., Blanchard, A. P., Elisma, F., Granger, M., Xu, H., Bennett, S. A. L., Figeys, D. and Zou, H. (2013), Phosphoproteome analysis of an early onset mouse model (TgCRND8) of Alzheimer's disease reveals temporal changes in neuronal and glia signaling pathways. Proteomics, 13: 1292–1305. doi: 10.1002/pmic.201200415
Colour Online: See the article online to view Figs. , and in colour.
- Issue online: 12 APR 2013
- Version of Record online: 2 APR 2013
- Accepted manuscript online: 18 JAN 2013 04:06AM EST
- Manuscript Accepted: 8 NOV 2012
- Manuscript Revised: 19 OCT 2012
- Manuscript Received: 8 SEP 2012
- NSFC. Grant Numbers: 21021004, 81161120540
- CIHR. Grant Numbers: CCI-117960, TGF-96121
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Figure S1. Phosphopeptide log2 ratio distribution quantified by pseudo triplex stable isotope dimethyl labelling with a CV ≤ 40% filtering (the sample labelling amounts ratio is (L/M/H) = (1/1/1), and 200 μg of each labelled sample was used for phosphopeptides enrichment).
Figure S2. Distribution of protein kinases predicted to be responsible for the phosphorylation in global phosphopeptides.
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