Quantitative proteomic analysis reveals the neuroprotective effects of huperzine A for amyloid beta treated neuroblastoma N2a cells
Version of Record online: 2 APR 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Special Issue: FOCUS ON INTEGRATIVE PROTEOMICS
Volume 13, Issue 8, pages 1314–1324, April 2013
How to Cite
Tao, Y., Fang, L., Yang, Y., Jiang, H., Yang, H., Zhang, H. and Zhou, H. (2013), Quantitative proteomic analysis reveals the neuroprotective effects of huperzine A for amyloid beta treated neuroblastoma N2a cells. Proteomics, 13: 1314–1324. doi: 10.1002/pmic.201200437
Colour Online: See the article online to view Figs. and in colour.
- Issue online: 12 APR 2013
- Version of Record online: 2 APR 2013
- Accepted manuscript online: 19 FEB 2013 12:01PM EST
- Manuscript Accepted: 26 NOV 2012
- Manuscript Revised: 25 NOV 2012
- Manuscript Received: 20 SEP 2012
- E-institutes of Shanghai Municipal Education Commission. Grant Number: E03008
- Shanghai Science and Technology Development Fund. Grant Number: 12QA1404000
- Ministry of Science and Technology of China. Grant Number: 2011CB510004
- National Natural Science Foundation of China. Grant Numbers: 81072646, 81173034
- Natural Science Foundation of Shanghai. Grant Number: 12ZR1436400
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Figure S1. Base peak chromatograms (A, B, C) and ion extract chromatograms (D, E, F) from the selected peptides of the 15 LC-MS/MS runs.
Figure S2. Subcellular location (A), isoelectric point pI (B), molecular weight MW (C), and GRAVY (D) distributions of our data, mouse brain tissue proteomic data (Ref. ) and proteins in IPI 3.87 database.
Figure S3. Scatter plots of the normalized LFQ intensity of each 198 proteins with p-value <0.05. (Y-axis: normalized LFQ intenstity)
Figure S4. Enriched KEGG pathway from the significant changed proteins.
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