New and improved proteomics technologies for understanding complex biological systems: Addressing a grand challenge in the life sciences


Correspondence: Dr. Gilbert S. Omenn, University of Michigan, 2065 Palmer Commons, Ann Arbor, MI 48109–2218, USA


Fax: +1 734-615-6553

Additional corresponding author: Dr. Leroy E. Hood



This White Paper sets out a Life Sciences Grand Challenge for Proteomics Technologies to enhance our understanding of complex biological systems, link genomes with phenotypes, and bring broad benefits to the biosciences and the US economy. The paper is based on a workshop hosted by the National Institute of Standards and Technology (NIST) in Gaithersburg, MD, 14–15 February 2011, with participants from many federal R&D agencies and research communities, under the aegis of the US National Science and Technology Council (NSTC). Opportunities are identified for a coordinated R&D effort to achieve major technology-based goals and address societal challenges in health, agriculture, nutrition, energy, environment, national security, and economic development.