Proteomics Comes of Age


Michael J. Dunn

With this issue, PROTEOMICS enters its fourteenth year of publication. The term “proteome” was coined by Marc Wilkins and introduced to the scientific community at the 1st Siena Meeting in 1994. The term proteome was originally defined as the “PROTEin complement of a genOME” but soon became to be generally accepted to mean the set of proteins expressed by a particular organelle, cell type, or tissue under a particular set of conditions. The 10th Biannual Siena Meeting to be held from 31st August to 4th September 2014 will mark the 20th Anniversary of the science of “proteomics”. The journal PROTEOMICS was first published in 2001 in response to the high level of interest shown in the application of proteomic approaches across a diverse range of areas of biological and biomedical research. The scientific community's interest in the field of proteomics shows little sign of abating. According to data from PubMed/MEDLINE, nearly 9,000 papers on the topic of proteomics were published in 2012. It is therefore not surprising that many more papers are submitted to PROTEOMICS than we can possibly publish on an annual basis, with the consequence that we must decline more than 50% of submissions. Our main aim continues to be to maintain PROTEOMICS as the premier source for information on all aspects of proteomics.

Over the last year it has again been a pleasure to work with the Editorial Steering Group of PROTEOMICS, made up of myself as Editor-in-Chief, our four Associate Editors, Thierry Rabilloud (Grenoble, France), Andrew Link (Nashville, TN, USA), Roz Banks (Leeds, UK) and Jennifer Van Eyk (Baltimore, MD, USA), together with Achim Kraus, Managing Editor of PROTEOMICS to help shape the future development of the journal to ensure that it remains a leader in the field. I would also like to thank our group of Senior Editors who have as always made a major contribution to the journal by coordinating the peer review process for all of the papers submitted to the journal. Finally, I would like to express our sincere thanks to the panel of around 730 Reviewers who have taken part in the peer review process of papers submitted to PROTEOMICS over the last 12 months. Their names can be found in the list that appears at the end of this issue.

It is now two years since we made any extensive revisions to the Editorial Board of PROTEOMICS. We believe that now is an appropriate time to revitalise the Editorial Board by recruiting some new members to join as from January 2014 (Volume 14). At this time we do not think that we should increase the number of Board members beyond its current level, so unfortunately I have had to ask a proportion of the current members to retire from the Editorial Board at this time. I would like to express my appreciation for the valuable input that these individuals have made as Board members to the development of the journal over the past years. I would now like to welcome the scientists who have accepted our invitation to join the Editorial Board of PROTEOMICS with effect from this issue. I am sure that their expertise and enthusiasm will enhance the journal in future. The names of the new members of the Editorial Board are: Ganesh Agrawal (Nepal), Kent Arrell (USA), Oliver Drews (Germany), Melanie Föcking (Ireland), Cecilia Gelfi (Italy), Rebekah Gundry (USA), Christof Rampitsch (Canada), Juan Antonio Vizcaino (UK), and Uwe Völker (Germany).

As of January 2013, we are publishing online a new set of Instructions to Authors for PROTEOMICS that includes some extensive additions and amendments. The new set of Instructions to Authors will be published in print in a future Issue of the journal. The requirements for full details of the experimental design and, where applicable, of patient groups and clinical samples have been expanded and made more rigorous. The need for data validation in comparative or shotgun-like discovery studies has been clarified. It is now mandatory that confirmatory data (e.g. from validated immunoassays, immunohistochemistry, alternative MS-based methods, Western blotting, etc.) using independent replication sets be provided for at least a subset of proteins. Deposition of supporting data in a public, and global open access database is strongly recommended for all types of manuscript and is mandatory for Dataset Briefs. Examples of such databases are the ProteomeXchange consortium ( [including the receiving repositories PRIDE and PASSEL] or World-2DPAGE ( For Dataset Briefs, placing of datasets only in private or institute websites is not acceptable, although the data can be deposited in both a global database and a private or institute website. Authors interested in submitting a manuscript to the journal are urged to consult carefully the current Instructions to Authors that can be found online. The current version of the Instructions to Authors is in HTML format with hyperlinks to different sections or other pages and can be seen at:

While the majority of the 24 issues of PROTEOMICS that will be published during 2014 will be regular issues, we will continue our policy of producing Special Issues devoted to collections of papers covering important and emerging areas of proteomics. In Volume 14 we will publish Special Issues on Top-down Proteomics (Editors: Ljiljana Pasa-Tolic, Christophe Masselon), Imaging Mass Spectrometry (Editor: José-Luis Capelo-Martínez), Recent Developments in Proteomics (Editor: Albert Sickmann), and Epigenetics and Chromatin Biology (Editors: Tom Vondriska, Ole Jensen). In addition, we will continue our tradition of having an annual issue devoted to reviews of hot topics in the field, to be published as a double issue 4/5 of Volume 14. We are already planning the Reviews issue of PROTEOMICS for Volume 15 (2015) – see the Call for Reviews published in this issue.

Readers of PROTEOMICS should regularly visit the journal homepage on Wiley Online Library ( to access the latest issue of the journal and to find specific articles, especially those published as “Epubs” (Accepted Articles, Early View) well before their appearance in a specific issue of the journal. Furthermore you can explore the many additional features, such as Book Reviews, Commentary Archive, Special Issue Archive, Meetings Diary and Viewpoint Forum that are updated regularly by our Web Editor, Christine Mayer. These features can be accessed by selecting items from the menu ‘‘Special Features’’.

Finally, I would like to thank the Associate Editors, Senior Editors, Editors of Special Issues, the Editorial Board and the members of the editorial team, and in particular the Managing Editor, Achim Kraus, and his team in the Editorial Office for their efforts over the last year to maintain PROTEOMICS as the most comprehensive journal in the field. I hope that researchers will continue to choose PROTEOMICS as the journal in which to publish the results of their research. Finally, I would like to thank you, the readers, for your continued support of PROTEOMICS and hope that you will find much to stimulate and interest you in PROTEOMICS during 2014.


Michael J. Dunn