Review Commentary

Mass spectrometry as a tool in dendrimer chemistry: from self-assembling dendrimers to dendrimer gas-phase host–guest chemistry†

  1. Christoph A. Schalley1,*,
  2. Bilge Baytekin1,
  3. H. Tarik Baytekin1,
  4. Marianne Engeser2,
  5. Thorsten Felder1,2,
  6. Alexander Rang1,2

Article first published online: 11 AUG 2006

DOI: 10.1002/poc.1105

Issue

Journal of Physical Organic Chemistry

Journal of Physical Organic Chemistry

Special Issue: ESOR X – 10th European Symposium On Organic Reactivity, 25–30 July 2005, Rome, Italy

Volume 19, Issue 8-9, pages 479–490, August - September 2006

Additional Information

How to Cite

Schalley, C. A., Baytekin, B., Baytekin, H. T., Engeser, M., Felder, T. and Rang, A. (2006), Mass spectrometry as a tool in dendrimer chemistry: from self-assembling dendrimers to dendrimer gas-phase host–guest chemistry. Journal of Physical Organic Chemistry, 19: 479–490. doi: 10.1002/poc.1105

Author Information

  1. 1

    Institut für Chemie und Biochemie der Freien Universität Berlin, Organische Chemie, Takustr. 3, D-14195 Berlin, Germany

  2. 2

    Kekulé-Institut für Organische Chemie und Biochemie der Universität Bonn, Gerhard-Domagk-Str. 1, D-53121 Bonn, Germany

*Institut für Chemie und Biochemie der Freien Universität Berlin, Organische Chemie, Takustr. 3, D-14195 Berlin, Germany.

  1. †

    Selected paper presented at the 10th European Symposium on Organic Reactivity, 25–30 July 2005, Rome, Italy

Publication History

  1. Issue published online: 14 DEC 2006
  2. Article first published online: 11 AUG 2006
  3. Manuscript Accepted: 10 APR 2006
  4. Manuscript Revised: 8 APR 2006
  5. Manuscript Received: 2 JAN 2006

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (1612K)

Keywords:

  • supramolecular chemistry;
  • mass spectrometry;
  • gas-phase chemistry;
  • dendrimers;
  • self-assembly;
  • molecular tweezers;
  • defects;
  • fragmentation mechanisms;
  • dendritic effects

Graphical Abstract

Thumbnail image of graphical abstract

Mass Spectrometry is a powerful tool to study various aspects of dendrimer chemistry including dendrimer self-assembly, their fragmentation behavior, and their host-guest chemistry in the gas phase.

Abstract

Mass spectrometry has played a significant role in dendrimer chemistry, because it serves as an excellent analytical means to determine the purity and analyze the nature of defects even for higher generations. However, a mass spectrometer can also be used as a laboratory to study isolated dendrimer molecules in the gas phase or their host–guest complexes. Since the properties of molecules under environment-free conditions are often quite different from those in solution, their gas-phase chemistry provides valuable new insight into properties which cannot easily be studied in solution. This article summarizes some of our work on characterizing self-assembling metallo-supramolecular dendrimers, on analyzing ionization artifacts, on the differentiation between several, sometimes even isomeric defects through tandem MS experiments, and finally on the analysis of a surprisingly clear dendritic effect occurring in the fragmentation of dendritic host–guest complexes. Copyright © 2006 John Wiley & Sons, Ltd.

Get PDF (1612K)