Article

Characterization of different poly(2-oxazoline) block copolymers by MALDI-TOF MS/MS and ESI-Q-TOF MS/MS

  1. Anja Baumgaertel1,2,
  2. Esra Altuntaş1,2,
  3. Kristian Kempe1,
  4. Anna Crecelius1,2,
  5. Ulrich S. Schubert1,2,*

Article first published online: 15 OCT 2010

DOI: 10.1002/pola.24364

Issue

Journal of Polymer Science Part A: Polymer Chemistry

Journal of Polymer Science Part A: Polymer Chemistry

Volume 48, Issue 23, pages 5533–5540, 1 December 2010

Additional Information

How to Cite

Baumgaertel, A., Altuntaş, E., Kempe, K., Crecelius, A. and Schubert, U. S. (2010), Characterization of different poly(2-oxazoline) block copolymers by MALDI-TOF MS/MS and ESI-Q-TOF MS/MS. J. Polym. Sci. A Polym. Chem., 48: 5533–5540. doi: 10.1002/pola.24364

Author Information

  1. 1

    Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Humboldtstr. 10, 07743 Jena, Germany

  2. 2

    Dutch Polymer Institute (DPI), John F. Kennedylaan 2, 5612 AB Eindhoven, The Netherlands

*Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Humboldtstr. 10, 07743 Jena, Germany

Publication History

  1. Issue published online: 28 OCT 2010
  2. Article first published online: 15 OCT 2010
  3. Manuscript Accepted: 31 AUG 2010
  4. Manuscript Received: 22 AUG 2010

Funded by

  • Thüringer Kultusministerium. Grant Numbers: B515-07008, B715-08011
  • Landesgraduiertenförderung Thüringen

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Keywords:

  • block copolymers;
  • ESI;
  • MALDI;
  • poly(2-oxazoline);
  • mass spectrometry

Abstract

A complete library of poly(2-oxazoline) block copolymers was synthesized via cationic ring opening polymerization for the characterization by two different soft ionization techniques, namely matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-Q-TOF MS). In addition, a detailed characterization was performed by tandem MS to gain more structural information about the block copolymer composition and its fragmentation behavior. The fragmentation of the poly(2-oxazoline) block copolymers revealed the desired polymer structure and possible side reactions, which could be explained by different mechanisms, like 1,4-ethylene or hydrogen elimination and the McLafferty +1 rearrangement. Polymers with aryl side groups showed less fragmentation due to their higher stability compared to polymers with alkyl side groups. These insights represent a further step toward the construction of a library with fragments and their fragmentation pathways for synthetic polymers, following the successful examples in proteomics. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010

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