Various brush polymers through ring opening metathesis polymerization and nitroxide radical coupling reaction



A 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-terminated poly(ethylene glycol) (PEG) or -poly(ε-caprolactone) (PCL) (PEG11-TEMPO or PCL23-TEMPO) is grafted as a side chain onto a ROMP-generated polyoxanorbornene (PONB) main backbone with bromide pendant groups (PONB20-Br) using the NRC click reaction to yield related the brush copolymers, PONB20-g-PEG11 or PONB20-g-PCL23 catalyzed by Cu(I), Cu(0), and N,N,N,N,N″-pentamethyldiethylenetriamine in N,N-dimethylformamide at room temperature. Additionally, a ROMP-generated brush copolymer PONB9-g-poly(methyl methacrylate)24 (PMMA)24-Cl was reacted with a PEG11-TEMPO or a PCL23-TEMPO precursor via the NRC click reaction to yield a corresponding brush terpolymer, PONB9-g-(PMMA24-b-PEG11) or PONB9-g-(PMMA24-b-PCL23) under a similar reaction condition described above. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011