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Inside Cover, Volume 50, Issue 5


Abstract

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Polymeric films with porous structures and microsphere patterns are prepared by the method of breath figures, mixing poly(methyl methacrylate) (PMMA) and amphiphilic copolymers containing glucose moieties in their structure, glycopolymers, as presented by Juan Rodríguez-Hernández and colleagues on page 851. Depending on experimental conditions (water content, humidity, and type of copolymer), the observed final film morphology changes significantly. Thus, films with honeycomb-patterned structures, spherical particles, or a mixture of both are obtained. In addition, polar glucose moieties are oriented principally either inside of the pores in the case of films and towards the surface in the case of particles. The specific surface bioactivity of these materials is examined using Con A-FITC, where successful binding of Con A is demonstrated by more intense fluorescence at the surface of the pores and of the particles.

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