As presented by Marta Fernández-García et al. on page 1337, two series of amphiphilic di- and triblock glycopolymers obtained by controlled radical polymerization directly using an unprotected glycomonomer are displayed. Some of these block glycopolymers, depending on the length of hydrophilic segment, can be water soluble and then self-aggregate as micelles. In addition to these solution properties, they can specifically bind with Concanavalin A lectin. It is important to mention that those block glycopolymers based on poly(methyl methacrylate) (PMMA) seem to be more suitable to this lectin than those with poly(n-butyl acrylate) (PBA).