• conducting polymers;
  • indole;
  • multiwalled carbon nanotubes;
  • nanocomposites;
  • sensors


A novel nanostructured conducting polymer (PICA-MWNTs) is easily prepared by direct electrodeposition of indole-6-carboxylic acid (ICA) and carboxylic groups ended multiwalled carbon nanotubes (MWNTs) in acetonitrile in one step. The resulting PICA-MWNTs composites with larger specific surface area and quite a few functionalized carboxylic acid groups are naturally integrated as a continuous uniform film on the electrode. CdSe quantum dots electrochemiluminescence biosensor with high sensitivity for detection of Ramos cells is fabricated based on PICA-MWNTs. Coupled with nanoparticle-amplification technnique, this sensor shows high sensitivity and good selectivity for Ramos cells with a low detection limit of 390 cells mL−1. This result provides an avenue for a simple and sensitive approach for detection of Ramos cells, which may have great potential in clinical applications. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 2385–2392