Preparation of antimicrobial poly(vinyl alcohol) nanofibers containing silver nanoparticles

Authors

  • Kyung Hwa Hong,

    1. Intelligent Textile System Research Center and School of Materials Science and Engineering, Seoul National University, Seoul 151-742, South Korea
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  • Jong Lyoul Park,

    1. Intelligent Textile System Research Center and School of Materials Science and Engineering, Seoul National University, Seoul 151-742, South Korea
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  • In Hwan Sul,

    1. Intelligent Textile System Research Center and School of Materials Science and Engineering, Seoul National University, Seoul 151-742, South Korea
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  • Ji Ho Youk,

    Corresponding author
    1. Department of Textile Engineering, Inha University, Incheon 402-751, South Korea
    • Department of Textile Engineering, Inha University, Incheon 402-751, South Korea
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  • Tae Jin Kang

    Corresponding author
    1. Intelligent Textile System Research Center and School of Materials Science and Engineering, Seoul National University, Seoul 151-742, South Korea
    • Intelligent Textile System Research Center, Seoul National University, Seoul 151-742, South Korea
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Abstract

Polyvinyl alcohol (PVA) nanofibers containing Ag nanoparticles were prepared by electrospinning PVA/silver nitrate (AgNO3) aqueous solutions, followed by short heat treatment, and their antimicrobial activity was investigated for wound dressing applications. Since PVA is a water soluble and biocompatible polymer, it is one of the best materials for the preparation of wound dressing nanofibers. After heat treatment at 155 °C for 3 min, the PVA/AgNO3 nanofibers became insoluble, while the Ag+ ions therein were reduced so as to produce a large number of Ag nanoparticles situated preferentially on their surface. The residual Ag+ ions were reduced by subsequent UV irradiation for 3 h. The average diameter of the Ag nanoparticles after the heat treatment was 5.9 nm and this value increased slightly to 6.3 nm after UV irradiation. It was found that most of the Ag+ ions were reduced by the simple heat treatment. The PVA nanofibers containing Ag nanoparticles showed very strong antimicrobial activity. © 2006 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 44: 2468–2474, 2006

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