Antibacterial and biocompatible surfaces based on dopamine autooxidized silver nanoparticles

Authors

  • Manthiriyappan Sureshkumar,

    1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
    2. Department of Chemistry, The University of Suwon, Gyeonggi-do, South Korea
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  • Dessy Yovita Siswanto,

    1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
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  • Yong-Cin Chen,

    1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
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  • Cheng-Kang Lee,

    Corresponding author
    1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
    • Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
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  • Meng-Jiy Wang

    Corresponding author
    1. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
    • Department of Chemical Engineering, National Taiwan University of Science and Technology, 43, Keelung Rd., Sec. 4, Taipei 106, Taiwan
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  • This article was published online on 14 November 2012. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected 27 November 2012.

Abstract

A facile and green method is proposed to immobilize silver nanoparticles (AgNPs) showing antibacterial and biocompatible properties on surfaces of substrates. The adhesive and reductive polydopamine (Pdop) coating was applied on the substrates such as polyethylene, glass, poly(methyl methacrylate), and poly(lactic-co-glycolic acid) by simply dipping into dopamine solutions. AgNPs of 50–70 nm formed uniformly on the Pdop-coated surfaces after immersing in silver nitrate solution where the density of AgNPs was modulated by Pdop immobilization time. Antibacterial efficacy, lactate dehydrogenase assay, and cell morphology observed by microscopy indicated that the as-prepared AgNPs deposited on Pdop/substrates possessed effective biocidal properties and did not inhibit the growth of L-929 cells mouse fibroblasts. The proposed method can be easily applied on different substrates and revealed good biocompatibility, which could be further developed for applications in biomaterials. © 2012 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2013

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