S. Simeonova, M. Evstatiev, W. Li and T. Burkhart
The creation of biodegradable scaffolds for tissue engineering often involves the use of toxic solvents, which, if not completely removed during processing, are harmful to cells. In this work, biodegradable polymer scaffolds are produced using a microfibrillar reinforced composites (MFC) manufacturing concept. Poly(L-lactide) fibrils are isolated from drawn polymer blends with nontoxic residual solvent. The MFC is adapted in the sense that, instead of melting the lower-melting component during processing, selective extraction of one of the blend constituents is applied.