Quality of life of patients with gastric cancer in Taiwan: validation and clinical application of the Taiwan Chinese version of the EORTC QLQ-C30 and EORTC QLQ-STO22

Authors

  • Chi-Cheng Huang,

    1. Division of General Surgery, Department of Surgery, Cathay General Hospital Sijhih, Taiwan
    2. School of Medicine, College of Medicine, Fu Jen Catholic University, Taiwan
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  • Heng-Hui Lien,

    1. School of Medicine, College of Medicine, Fu Jen Catholic University, Taiwan
    2. Division of General Surgery, Department of Surgery, Cathay Medical Center, Taiwan
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  • Yung-Chuan Sung,

    1. School of Medicine, College of Medicine, Fu Jen Catholic University, Taiwan
    2. Division of Hematology and Oncology, Department of Internal Medicine, Cathay Medical Center, Taiwan
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  • Han-Ting Liu,

    1. Division of Hematology and Oncology, Department of Internal Medicine, Cathay Medical Center, Taiwan
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  • Wei-Chu Chie

    Corresponding author
    1. Department of Public Health and Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taiwan
    • School of Public Health and Graduate Institute of Preventive Medicine, College of Public Health, National Taiwan University, Room 520, 17 Xuzhou Road, Taipei 10055, Taiwan
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Abstract

The relatively high incidence of gastric cancer in Taiwan warranted the need of a disease-specific quality of life (QOL) instrument. We translated the EORTC QLQ-C30 and QLQ-STO22 according to the guidelines from the EORTC. A total of 100 patients were interviewed. Convergent and discriminant validity, Cronbach's alpha coefficient and known-groups comparisons were used to examine the reliability and validity. We found good reliability for multi-item subscales of the QLQ-C30 and QLQ-STO22 (Cronbach's alpha coefficient: 0.70–0.94) except cognitive functioning of the QLQ-C30 and eating restriction of the QLQ-STO22. Patients in the active treatment group experienced compromised functional status and worse treatment-associated symptoms than those in the follow-up group. Similar results were found in comparisons based on Eastern Cooperative Oncology Group (ECOG) Performance Status and dysphagia grades. The study has ascertained the cross-cultural validity, reliability and clinical applicability of the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-STO22. Copyright © 2007 John Wiley & Sons, Ltd.

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