Antecedents of domain-specific quality of life after colorectal cancer
Article first published online: 11 JUL 2008
Copyright © 2008 John Wiley & Sons, Ltd.
Volume 18, Issue 2, pages 216–220, February 2009
How to Cite
Steginga, S. K., Lynch, B. M., Hawkes, A., Dunn, J. and Aitken, J. (2009), Antecedents of domain-specific quality of life after colorectal cancer. Psycho-Oncology, 18: 216–220. doi: 10.1002/pon.1388
- Issue published online: 30 JAN 2009
- Article first published online: 11 JUL 2008
- Manuscript Accepted: 9 APR 2008
- Manuscript Revised: 30 MAR 2008
- Manuscript Received: 12 DEC 2007
- quality of life;
- cancer survivorship
Objective: The present study prospectively assessed the influence of medical, socio-demographic, psychological, and lifestyle variables on physical, social/family, emotional, functional well-being and colorectal cancer-specific concerns in a population-based sample of colorectal cancer survivors.
Methods: Participants (n=1822) were assessed at 6 and 24 months post-diagnosis. Predictor variables assessed at 6 months included socio-demographic and medical variables, symptoms/side-effects, body mass index, physical activity, optimism, social support, and cancer threat appraisal. Quality of life (QOL) was assessed at 6 and 24 months post-diagnosis using the Functional Assessment of Cancer Therapy - Colorectal (FACT-C).
Results: For each QOL subscale and for the overall FACT-C scale, 6 month scores were the strongest predictor of QOL scores at 24 months post-diagnosis (e.g. β=0.447, p < 0.001 for overall QOL). Socio-demographic, medical, and psychosocial variables, but not lifestyle variables, differentially predicted domain specific QOL. Only cancer threat appraisal was associated with all five QOL domains.
Conclusion: Cancer threat appraisal presents as a potentially modifiable variable for interventions seeking to improve QOL. Symptom management and lifestyle strategies to ameliorate the effects of co-morbidities, disease stage and troublesome symptoms such as faecal incontinence on QOL should also be included. Copyright © 2008 John Wiley & Sons, Ltd.