Mindfulness-based cognitive therapy reduces chronic cancer-related fatigue: a treatment study
Article first published online: 19 DEC 2010
Copyright © 2010 John Wiley & Sons, Ltd.
Volume 21, Issue 3, pages 264–272, March 2012
How to Cite
van der Lee, M. L. and Garssen, B. (2012), Mindfulness-based cognitive therapy reduces chronic cancer-related fatigue: a treatment study. Psycho-Oncology, 21: 264–272. doi: 10.1002/pon.1890
- Issue published online: 1 MAR 2012
- Article first published online: 19 DEC 2010
- Manuscript Accepted: 31 OCT 2010
- Manuscript Revised: 29 OCT 2010
- Manuscript Received: 5 NOV 2009
- cancer-related fatigue;
Introduction: About one-third of cancer survivors suffer from severe chronic fatigue. Aim of this study was to evaluate the efficacy of mindfulness-based cognitive group therapy in reducing severe chronic fatigue in cancer survivors with mixed diagnoses.
Patients and Methods: Participants (n = 100) were randomly selected from a cohort and allocated to an intervention and a waiting list condition. Analyses were based on 59 participants in the intervention condition and 24 in the waiting-list condition. Fatigue severity (Checklist Individual Strength), functional impairment (Sickness Impact Profile) and well being (Health and Disease-Inventory) were assessed before and after the 9-week intervention. The intervention group had a follow-up 6 months following the intervention.
Results: At post-treatment measurement the proportion of clinically improved participants was 30%, versus 4% in the waiting list condition (χ2 (1) = 6.71; p = 0.007). The mean fatigue score at post-measurement was significantly lower in the intervention group than in the waiting list group corrected for pre-treatment level of fatigue. The mean well-being score at post-measurement was significantly higher in the intervention group than in the waiting list group corrected for pre-treatment level of well-being. The treatment effect was maintained at 6-month follow-up. No difference between the two conditions was found in functional impairment.
Discussion: Mindfulness-based cognitive therapy is an effective treatment for chronic cancer-related fatigue. Copyright © 2010 John Wiley & Sons, Ltd.