Moderators of cancer-related distress and worry after a pancreatic cancer genetic counseling and screening intervention
Article first published online: 20 JUL 2011
Copyright © 2011 John Wiley & Sons, Ltd.
Volume 21, Issue 12, pages 1324–1330, December 2012
How to Cite
Hart, S. L., Torbit, L. A., Crangle, C. J., Esplen, M. J., Holter, S., Semotiuk, K., Borgida, A., Ardiles, P., Rothenmund, H. and Gallinger, S. (2012), Moderators of cancer-related distress and worry after a pancreatic cancer genetic counseling and screening intervention. Psycho-Oncology, 21: 1324–1330. doi: 10.1002/pon.2026
- Issue published online: 4 DEC 2012
- Article first published online: 20 JUL 2011
- Manuscript Accepted: 11 JUN 2011
- Manuscript Revised: 8 JUN 2011
- Manuscript Received: 16 FEB 2011
- genetic counseling;
- psychological distress;
Although the hereditary breast and ovarian cancer literature has demonstrated short-term gains in psychological adjustment following genetic counseling, there has been limited research examining long-term outcomes and moderators. Moreover, there has been minimal research into the psychological effects of this intervention in populations at high risk for pancreatic cancer. This study examines the long-term effects of pancreatic cancer screening and genetic counseling on cancer-related distress and cancer worry in a high-risk population at 1-year follow-up. Additionally, this study explores potential moderators of the effectiveness of this intervention.
One hundred twenty-nine participants with familial pancreatic cancer or with the BRCA2 gene mutation completed a baseline questionnaire prior to their first pancreatic cancer screening and genetic counseling session. Participants also completed questionnaires at 3- and 12-month follow-up.
Cancer-related intrusive thoughts decreased significantly over time, whereas cancer-related worry decreased at 3 months and showed a small but significant increase at 1 year. Age and baseline distress exhibited moderator effects. Younger individuals showed a significant decrease in cancer-related intrusive thoughts, cancer-related avoidant thoughts, and cancer worry. Additionally, individuals with greater baseline distress showed a significant decrease in cancer-related intrusive thoughts over time.
Analysis of the long-term effects of pancreatic cancer screening and genetic testing reveal psychological gains that are maintained at 1-year follow-up. This intervention is particularly effective for younger participants and individuals with greater baseline distress. Copyright © 2011 John Wiley & Sons, Ltd.