Gender differences in health-related quality of life, physical function and psychological status among patients in the early phase following allogeneic haematopoietic stem cell transplantation
Article first published online: 27 JUN 2012
Copyright © 2012 John Wiley & Sons, Ltd.
Volume 22, Issue 5, pages 1159–1166, May 2013
How to Cite
Morishita, S., Kaida, K., Yamauchi, S., Wakasugi, T., Yoshihara, S., Taniguchi, K., Ishii, S., Ikegame, K., Kodama, N., Ogawa, H. and Domen, K. (2013), Gender differences in health-related quality of life, physical function and psychological status among patients in the early phase following allogeneic haematopoietic stem cell transplantation. Psycho-Oncology, 22: 1159–1166. doi: 10.1002/pon.3128
- Issue published online: 6 MAY 2013
- Article first published online: 27 JUN 2012
- Manuscript Accepted: 7 JUN 2012
- Manuscript Revised: 22 MAY 2012
- Manuscript Received: 8 MAR 2012
- allogeneic haematopoietic stem cell transplantation;
- gender differences;
- quality of life;
- physical function
The aim of this study was to examine gender differences in quality of life (QOL), physical function and psychological status before and in the early phase after allogeneic haematopoietic stem cell transplantation (allo-HSCT).
One hundred patients (66 men, 34 women) who underwent allo-HSCT between July 2007 and June 2011 at Hyogo College of Medicine Hospital were included in this study. Patients were evaluated for health-related QOL using the Medical Outcome Study 36-item Short Form Health Survey; exercise capacity was measured with the 6-min walk test, hand grip strength and knee extensor strength. Fatigue and psychological status were measured by the Piper Fatigue Scale and Hospital Anxiety and Depression Scale, respectively.
Women had significantly lower scores for physical function and general health on health-related QOL tests compared with men (p < 0.01). No difference between genders was found in decline of physical function. In women, exercise capacity was strongly associated with QOL (p < 0.01). In men, depression and anxiety were closely related to QOL (p < 0.01).
Gender-appropriate rehabilitation in allo-HSCT patients is important. Women may need more endurance exercises and training for activities of daily life. Men may need rehabilitation including a psychological approach. Copyright © 2012 John Wiley & Sons, Ltd.