Surface Functionalization of COC Microfluidic Materials by Plasma and Click Chemistry Processes (pages 959–969)
Yoann Ladner, Fanny d'Orlyé, Camille Perréard, Bradley Da Silva, Cédric Guyon, Michael Tatoulian, Sophie Griveau, Fethi Bedioui and Anne Varenne
Article first published online: 15 AUG 2013 | DOI: 10.1002/ppap.201300066
A robust method for COC functionalization was developed for the first time by plasma polymerization, providing brominated functionalities, further functionalized by surface “click” chemistry. The successful immobilization of a fluorescent alkyne demonstrated an excellent robustness, homogeneity and high surface reactivity of brominated deposits. This opens the way to incorporating different functional groups on COC surfaces, for the development of COC microchip.