Adhesion of U-937 Monocytes on Different Amine-functionalised Polymer Surfaces (pages 243–252)
Amélie St-Georges-Robillard, Juan-Carlos Ruiz, Alain Petit, Hong Tian Wang, Fackson Mwale, Bentsian Elkin, Christian Oehr, Sophie Lerouge and Michael R. Wertheimer
Version of Record online: 23 DEC 2011 | DOI: 10.1002/ppap.201100128
Human U-937 monocytes do not adhere to normally cell-adhering surfaces, e.g. tissue-culture poly(styrene). We reported that organic thin films did facilitate the adhesion and proliferation of U-937, provided that the concentration of primary amines exceed a critical value, [NH2]crit ≥ 4.2 at.%. That criterion being satisfied by pristine Parylene diX AM, we have compared its performance with L-PPE:N and UV-PE:N, particular types of PVP:N. We report aging of these coating types in atmospheric air, then of time-dependent adhesion of U-937 cells. The coatings manifest interesting differences that so far elude detailed understanding.