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Thermo-Responsive Multi-Cargo Core Shell Particles

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Combining formulation of particle-stabilized water-in-oil-in-water emulsion and in situ sol-gel chemistry, original monodisperse thermo-responsive capsules able to encapsulate at once hydrophilic and hydrophobic drugs are synthesized. Due to the presence of a stiff shell, the release is provoked by increasing the temperature above the wax melting point. The solid-to-liquid transition induces a volume expansion responsible for the capsule rupture.

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