[+]Present address: Maharashtra Institute of Pharmacy MIT Campus, Paud Road, Pune-411038, India
Fabrication of pH-Tunable Calcium Phosphate Nanocapsules via Dendrimer-Templated Assembly for Intracellular Lysosomal Release of Drugs
Article first published online: 22 MAR 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Particle & Particle Systems Characterization
Volume 30, Issue 6, pages 494–500, June 2013
How to Cite
Khandare, J. J., Jalota-Badhwar, A., Taneja, N., Mascarenhas, R. R., Vadodaria, K., Zope, K. R. and Banerjee, S. S. (2013), Fabrication of pH-Tunable Calcium Phosphate Nanocapsules via Dendrimer-Templated Assembly for Intracellular Lysosomal Release of Drugs. Part. Part. Syst. Charact., 30: 494–500. doi: 10.1002/ppsc.201300034
- Issue published online: 19 JUN 2013
- Article first published online: 22 MAR 2013
- Manuscript Revised: 15 FEB 2013
- Manuscript Received: 29 JAN 2013
- Piramal Life Science Ltd.
- drug delivery;
- calcium phosphate;
A pH-responsive dendrimer templated polymer-calcium phosphate core shell nanostructure is developed. Upon exposure to cellular lysosomal pH, a guest anticancer drug is released from the nanocapsule by dissolution of the CaP shell. Such a stimuli responsive carrier enables on-demand controlled release of drugs in acidic organelles.