Drug Delivery: Multifunctional Polymer-Coated Carbon Nanotubes for Safe Drug Delivery (Part. Part. Syst. Charact. 4/2013)




Poly(lactide)-co-poly(ethylene glycol) coated carbon nanotubes are used for controlled delivery of paclitaxel. Thomas Moore and co-workers on page 365 report multifunctional polymer coated carbon nanotubes coated with biodegradable and biocompatible polymers to encapsulate and deliver drugs for a prolonged period of time. Furthermore, the coatings reduce in vitro cytotoxicity and in vivo systemic toxicity of carbon nanotubes, which is critical for intravenous administration. Image credit: Robert R. Johnson (University of Pennsylvania)