Get access

Waist circumference, BMI, and lung function in 8-year-old children: The PIAMA birth cohort study

Authors

  • Marga B.M. Bekkers PhD,

    Corresponding author
    1. Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands
    2. Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
    • National Institute for Public Health and the Environment (RIVM), Centre for Prevention and Health Services Research (pb 101), PO Box 1, 3720 BA Bilthoven, The Netherlands.
    Search for more papers by this author
  • Alet H. Wijga PhD,

    1. Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
    Search for more papers by this author
  • Johan C. de Jongste MD, PhD,

    1. Department of Pediatrics, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands
    Search for more papers by this author
  • Marjan Kerkhof PhD,

    1. Department of Epidemiology and Bioinformatics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Search for more papers by this author
  • Dirkje Postma MD, PhD,

    1. Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Search for more papers by this author
  • Ulrike Gehring PhD,

    1. Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands
    Search for more papers by this author
  • Henriëtte A. Smit PhD,

    1. Julius Centre for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Search for more papers by this author
  • Bert Brunekreef PhD

    1. Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands
    2. Julius Centre for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Search for more papers by this author

  • Conflict of interest: None.

Abstract

Background

Body mass index (BMI) and waist circumference (WC) may be associated with lung function in children, as observed in adults.

Methods

Height, weight, waist circumference, and lung function (FVC and FEV1) were measured during a medical examination in 1,058 eight-year-old children participating in the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort study.

Results

After adjusting for height, age and other potential confounders large WC or high BMI (>90th percentile) were not associated with forced expiratory volume in 1 sec (FEV1) or forced vital capacity (FVC). In girls only, large WC was, independently of BMI, associated with 3.5% (95% confidence interval (CI): −6.4, −0.6) lower FEV1/FVC ratio in the model including WC and BMI. Girls with low BMI (<10th percentile) had 4.6% lower FEV1 (95% CI: −8.4, −0.6) and 5.1% lower FVC (95% CI: −8.8, −1.2) than girls with normal BMI. In boys, we did not observe associations between low or high BMI and lung function independent of WC, or between small or large WC and lung function after adjustment for BMI.

Conclusion

At 8 years of age, a high BMI or large WC are not yet associated with FEV1 and FVC, indicating that this association may change over the course of life from childhood to adulthood. Pediatr Pulmonol. 2013; 48:674–682. © 2012 Wiley Periodicals, Inc.

Ancillary