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References

  • 1
    Hsiang YH, Hertzberg R, Hecht S, Liu LF ( 1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260: 1487314878.
  • 2
    Hsiang YH, Liu LF ( 1988) Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48: 17221726.
  • 3
    Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB,Jr, Stewart L ( 2002) The mechanism of topoisomerase I poisoning by a camptothecin analog. Proc Natl Acad Sci USA 99: 1538715392.
  • 4
    Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G ( 2002) Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res 62: 43164324.
  • 5
    Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G ( 2004) Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res 64: 14751482.
  • 6
    Been MD, Burgess RR, Champoux JJ ( 1984) DNA strand breakage by wheat germ type 1 topoisomerase. Biochim Biophys Acta 782: 304312.
  • 7
    Kjeldsen E, Mollerup S, Thomsen B, Bonven BJ, Bolund L, Westergaard O ( 1988) Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage. J Mol Biol 202: 333342.
  • 8
    Porter SE, Champoux JJ ( 1989) Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules. Mol Cell Biol 9: 541550.
  • 9
    Jaxel C, Capranico G, Kerrigan D, Kohn KW, Pommier Y ( 1991) Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J Biol Chem 266: 2041820423.
  • 10
    Tanizawa A, Kohn KW, Pommier Y ( 1993) Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin. Nucleic Acids Res 21: 51575166.
  • 11
    Tanizawa A, Kohn KW, Kohlhagen G, Leteurtre F, Pommier Y ( 1995) Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives. Biochemistry 34: 72007206.
  • 12
    Jaxel C, Kohn KW, Pommier Y ( 1988) Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin. Nucleic Acids Res 16: 1115711170.
  • 13
    Porter SE, Champoux JJ ( 1989) The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. Nucleic Acids Res 17: 85218532.
  • 14
    Bonven BJ, Gocke E, Westergaard O ( 1985) A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin. Cell 41: 541551.
  • 15
    Valenti M, Nieves-Neira W, Kohlhagen G, Kohn KW, Wall ME, Wani MC, Pommier Y ( 1997) Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells. Mol Pharmacol 52: 8287.
  • 16
    Bailly C ( 2001) DNA relaxation and cleavage assays to study topoisomerase I inhibitors. Methods Enzymol 340: 610623.
  • 17
    Pondarre C, Strumberg D, Fujimori A, Torres-Leon R, Pommier Y ( 1997) In vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells. Nucleic Acids Res 25: 41114116.
  • 18
    Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG Crystal ( 1998) Structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science 279: 15041513.
  • 19
    Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ ( 1998) A model for the mechanism of human topoisomerase I. Science 279: 15341541.
  • 20
    Redinbo MR, Champoux JJ, Hol WG ( 2000) Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA. Biochemistry 39: 68326840.
  • 21
    Interthal H, Quigley PM, Hol WG, Champoux JJ ( 2004) The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J Biol Chem 279: 29842992.
  • 22
    Stewart L, Champoux JJ ( 1997) Purification of baculovirus-expressed human DNA topoisomerase I. Methods Mol Biol 94: 223234.