1469-896X/asset/olbannerleft.gif?v=1&s=d218899ae53b2862ab119790ed504b8d72122fb3)
1469-896X/asset/olbannerright.gif?v=1&s=59470eb9a1d9b7b13b1be75e9445e6c46ee2214f)
Article
You have full text access to this OnlineOpen article
Ion-specific modulation of protein interactions: Anion-induced, reversible oligomerization of a fusion protein
Article first published online: 2 DEC 2008
DOI: 10.1002/pro.20
Copyright © 2008 The Protein Society
Additional Information
How to Cite
Gokarn, Y. R., Fesinmeyer, R. M., Saluja, A., Cao, S., Dankberg, J., Goetze, A., Jr., R. L. R., Narhi, L. O. and Brems, D. N. (2009), Ion-specific modulation of protein interactions: Anion-induced, reversible oligomerization of a fusion protein. Protein Science, 18: 169–179. doi: 10.1002/pro.20
Publication History
- Issue published online: 16 DEC 2008
- Article first published online: 2 DEC 2008
- Accepted manuscript online: 2 DEC 2008 12:00AM EST
- Manuscript Accepted: 22 OCT 2008
- Manuscript Revised: 21 OCT 2008
- Manuscript Received: 24 JUL 2008
References
- 1( 1888) Zur Lehre von der Wirkung der Salze. Naunyn Schmiedebergs Arch Pharmacol 24: 247–260.
- 2, ( 1986) The systematic characterization by aqueous column chromatography of solutes which affect protein stability. J Biol Chem 261: 12477–12485.
- 3, ( 2002) Sulfate anion stabilization of native ribonuclease A both by anion binding and by the Hofmeister effect. Protein Sci 11: 1771–1778.Direct Link:
- 4, , , ( 2004) Role of protein-water interactions and electrostatics in alpha-synuclein fibril formation. Biochemistry 43: 3289–3300.
- 5, , , , , , , , ( 2005) Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability. Biochemistry 44: 1288–1299.
- 6, , , ( 2006) Sulfates dramatically stabilize a salt-dependent type of glucagon fibrils. Biophys J 90: 4181–4194.
- 7, , ( 1990) Anion-linked polymerization of the tetrameric hemoglobin from Scapharca inaequivalvis. Characterization and functional relevance. J Biol Chem 265: 6203–6209.
- 8, , ( 1996) Charge-shielding and the “paradoxical” stimulation of tubulin polymerization by guanidine hydrochloride. Biochemistry 35: 5910–5920.
- 9, , ( 1996) Cation selective promotion of tubulin polymerization by alkali metal chlorides. Protein Sci 5: 2020–2028.Direct Link:
- 10, , , ( 2005) Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution. J Pharm Sci 94: 1928–1940.Direct Link:
- 11, , , ( 2008) Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity. J Pharm Sci 97: 4219–4227.Direct Link:
- 12, , ( 1980) Anion chromatography with low-conductivity eluents. II. J Chromatogr 187: 35–45.
- 13, , ( 2000) Anion-induced stabilization of human serum albumin prevents the formation of intermediate during urea denaturation. Proteins 40: 29–38.Direct Link:
- 14, , ( 2000) Anion-induced refolding of human serum albumin under low pH conditions. Biochim Biophys Acta 1476: 139–148.
- 15( 1996) How Hofmeister ion interactions affect protein stability. Biophys J 71: 2056–2063.
- 16, ( 2006) Interactions between macromolecules and ions: the Hofmeister series. Curr Opin Chem Biol 10: 658–663.
- 17( 1995) Sticky ions in biological systems. Proc Natl Acad Sci USA 92: 5553–5557.
- 18( 1997) Charge density-dependent strength of hydration and biological structure. Biophys J 72: 65–76.
- 19( 2004) Ions from the Hofmeister series and osmolytes: effects on proteins in solution and in the crystallization process. Methods 34: 300–311.
- 20( 2006) Ion hydration: implications for cellular function, polyelectrolytes, and protein crystallization. Biophys Chem 119: 271–281.
- 21, , ( 2007) Ions in water: characterizing the forces that control chemical processes and biological structure. Biophys Chem 128: 95–104.
- 22, , , , , , , , , ( 1992) Altering the association properties of insulin by amino acid replacement. Protein Eng 5: 527–533.
- 23, , ( 2007) Insulin self-association: effects on lung disposition kinetics in the airways of the Isolated Perfused Rat Lung (IPRL). Pharm Res 24: 1636–1644.
- 24, , ( 2004) Challenges in the development of high protein concentration formulations. J Pharm Sci 93: 1390–1402.Direct Link:
- 25, , ( 2006) Protein aggregation and bioprocessing. AAPS J 8: E572–E579.
- 26( 2006) Effects of protein aggregates: an immunologic perspective. AAPS J 8: E501–E507.
- 27, , ( 1996) Self-association of spectrin's repeating segments. Biochemistry 35: 5257–5263.
- 28, , , ( 1986) Reversible self-association of bovine growth hormone during equilibrium unfolding. Biochemistry 25: 6533–6538.
- 29, , , , , ( 1998) Self-association properties of monomeric insulin analogs under formulation conditions. Pharm Res 15: 1434–1441.
- 30( 2003) Manipulating the reversible aggregation of protein hormones in secretory granules: potential impact on biopharmaceutical development. BioDrugs 17: 315–324.
- 31, , , ( 1999) Conformation and self-association of human recombinant transforming growth factor-beta3 in aqueous solutions. J Biol Chem 274: 7699–7704.
- 32, ( 1996) Reversible association of the cytokines MIP-1 alpha and MIP-1 beta with the endothelia of the blood-brain barrier. Neurosci Lett 205: 202–206.
- 33( 1997) Glycosylation is influential in murine IgG3 self-association. Mol Immunol 34: 593–598.
- 34, , ( 1999) Kinetics and thermodynamics of dimer formation and dissociation for a recombinant humanized monoclonal antibody to vascular endothelial growth factor. Biochemistry 38: 13960–13967.
- 35, , , , ( 2002) Reversible dimer formation and stability of the anti-tumour single-chain Fv antibody MFE-23 by neutron scattering, analytical ultracentrifugation, and NMR and FT-IR spectroscopy. J Mol Biol 320: 107–127.
- 36, , ( 2002) Surface plasmon resonance study on the interaction between lactose-installed poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles and lectins immobilized on a gold surface. Langmuir 18: 10334–10339.
- 37, , , , , ( 2006) Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. J Control Release 111: 107–116.
- 38, , , ( 2001) Non-ideality by sedimentation velocity of halophilic malate dehydrogenase in complex solvents. Biophys J 81: 1868–1880.
- 39, ( 1985) The Hofmeister effect and the behaviour of water at interfaces. Q Rev Biophys 18: 323–422.
- 40, , , ( 2005) An arginine residue in the pore region is a key determinant of chloride dependence in cardiac pacemaker channels. J Biol Chem 280: 13694–13700.
- 41, ( 1999) Cation-pi interactions in structural biology. Proc Natl Acad Sci USA 96: 9459–9464.
- 42, , , , , ( 1993) Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry 32: 9031–9037.
- 43( 2000) Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophys J 78: 1606–1619.
- 44( 2003) On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation. Anal Biochem 320: 104–124.