Article

Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease

  1. Oscar Alvizo1,†,
  2. Seema Mittal2,†,
  3. Stephen L. Mayo3,4,‡,
  4. Celia A. Schiffer2,‡,*

Article first published online: 5 JUN 2012

DOI: 10.1002/pro.2086

Issue

Protein Science

Protein Science

Volume 21, Issue 7, pages 1029–1041, July 2012

Additional Information

How to Cite

Alvizo, O., Mittal, S., Mayo, S. L. and Schiffer, C. A. (2012), Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease. Protein Science, 21: 1029–1041. doi: 10.1002/pro.2086

Author Information

  1. 1

    Division of Biology, Biochemistry and Molecular Biophysics Option, California Institute of Technology, Pasadena, California 91125

  2. 2

    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605

  3. 3

    Division of Biology, California Institute of Technology, Pasadena, California 91125

  4. 4

    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125

  1. †

    Oscar Alvizo and Seema Mittal contributed equally to this work.

  2. ‡

    Stephen L. Mayo and Celia A. Schiffer should be considered joint corresponding authors.

*Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605

  1. †

    Oscar Alvizo and Seema Mittal contributed equally to this work.

  2. ‡

    Stephen L. Mayo and Celia A. Schiffer should be considered joint corresponding authors.

Publication History

  1. Issue published online: 14 JUN 2012
  2. Article first published online: 5 JUN 2012
  3. Accepted manuscript online: 1 MAY 2012 04:04PM EST
  4. Manuscript Accepted: 10 APR 2012
  5. Manuscript Revised: 23 MAR 2012
  6. Manuscript Received: 18 JAN 2012

Funded by

  • National Institutes of Health. Grant Numbers: R01 GM064347, P01 GM66524
  • National Institutes of Health, National Center for Research Resources. Grant Number: RR007707
  • Office of Biological and Environmental Research
  • Office of Basic Energy Sciences of the US Department of Energy
  • National Center for Research Resources of the National Institutes of Health

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