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Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes

  1. A. Ullah1,‡,
  2. T. A. C. B. Souza2,‡,
  3. L. M. Zanphorlin1,†,
  4. R. B. Mariutti1,
  5. V. S. Santana1,
  6. M. T. Murakami2,
  7. R. K. Arni1,*

Article first published online: 13 DEC 2012

DOI: 10.1002/pro.2189

Issue

Protein Science

Protein Science

Volume 22, Issue 1, pages 128–132, January 2013

Additional Information

How to Cite

Ullah, A., Souza, T. A. C. B., Zanphorlin, L. M., Mariutti, R. B., Santana, V. S., Murakami, M. T. and Arni, R. K. (2013), Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes. Protein Science, 22: 128–132. doi: 10.1002/pro.2189

Author Information

  1. 1

    Multi User Center for Biomolecular Innovation, Department of Physics, IBILCE/UNESP, São Jose do Rio Preto, SP, Brazil

  2. 2

    Brazilian Biosciences National Laboratory (LNBio), CNPEM, Campinas, SP, Brazil

  1. †

    L. M. Zanphorlin's current address is Department of Chemistry, UNICAMP, Campinas, Brazil

  1. ‡

    A. Ullah and T. A. C. B. Souza contributed equally to this work.

*Departamento de Física, Universidade Estadual Paulista (UNESP), São José do Rio Preto, 15054-000, SP, Brasil

  1. ‡

    A. Ullah and T. A. C. B. Souza contributed equally to this work.

Publication History

  1. Issue published online: 13 DEC 2012
  2. Article first published online: 13 DEC 2012
  3. Accepted manuscript online: 8 NOV 2012 11:14AM EST
  4. Manuscript Accepted: 29 OCT 2012
  5. Manuscript Revised: 27 OCT 2012
  6. Manuscript Received: 28 AUG 2012

Funded by

  • FAPESP
  • CNPq
  • TWAS
  • DAAD
  • CAPES

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