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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
pro2281-sup-0001-suppfig1.tif100KSupporting Figure 1.
pro2281-sup-0002-suppfig2.tif144KSupporting Figure 2.
pro2281-sup-0003-suppfig3.tif1037KSupporting Figure 3.
pro2281-sup-0004-supptables.doc38KTable S1 Thermodynamic parameters of biotin binding to bradavidin II determined by competitive ITC. Desthiobiotin was used as a competitive ligand with the indicated concentrations.

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