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Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1
Article first published online: 16 SEP 2009
DOI: 10.1002/pro.240
Copyright © 2009 The Protein Society
Additional Information
How to Cite
Gui, C. and Hagenbuch, B. (2009), Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1. Protein Science, 18: 2298–2306. doi: 10.1002/pro.240
Publication History
- Issue published online: 23 OCT 2009
- Article first published online: 16 SEP 2009
- Accepted manuscript online: 16 SEP 2009 12:00AM EST
- Manuscript Accepted: 27 AUG 2009
- Manuscript Revised: 11 AUG 2009
- Manuscript Received: 6 JUL 2009
Funded by
- National Institute of Health. Grant Numbers: RR021940, GM077336
References
- 1, ( 2004) Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447: 653–665.
- 2, ( 2003) The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 1609: 1–18.
- 3, , , ( 2006) Pharmacogenomics of human OATP transporters. Naunyn Schmiedebergs Arch Pharmacol 372: 432–443.
- 4, , , , , , , , , , , ( 1999) Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem 274: 17159–17163.
- 5, , , , , , , , , , , , , , , , , , , , , , , , , , , , ( 2001) LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology 120: 1689–1699.
- 6, , , , , , ( 1999) A novel human hepatic organic anion transporting polypeptide (OATP2). J Biol Chem 274: 37161–37168.
- 7, , , ( 2000) A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am J Physiol 278: G156–G164.
- 8, , , ( 2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. J Biol Chem 275: 23161–23168.
- 9, ( 2008) Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family. Xenobiotica 38: 778–801.
- 10, , , , ( 2008) Topological assessment of oatp1a1: a 12-transmembrane domain integral membrane protein with three N-linked carbohydrate chains. Am J Physiol 294: G1052–G1059.
- 11, , , , , , , , ( 2001) Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120: 525–533.
- 12, , , , , , ( 2008) Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3. Eur J Pharmacol 584: 57–65.
- 13, , , , , , ( 2001) Hepatic uptake of cholecystikinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. Gastroenterology 121: 1185–1190.
- 14, , , , ( 2005) Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel. Cancer Biol Ther 4: 815–818.
- 15, ( 2008) Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport. Biochemistry 47: 9090–9097.
- 16, , , ( 2009) The 8th and 9th transmembrane domains in organic anion transporting polypeptide (OATP) 1B1 affect the transport kinetics of estrone-3-sulfate and estradiol-17{beta}-D-glucuronide. J Pharmacol Exp Ther 329: 551–557.
- 17, , , ( 2007) Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. Drug Metab Dispos 35: 1308–1314.
- 18, , , , , ( 2001) Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C. Pharm Res 18: 1262–1269.
- 19, , ( 1999) Mapping the substrate binding site of the prostaglandin transporter PGT by cysteine scanning mutagenesis. J Biol Chem 274: 25564–25570.
- 20, ( 2008) Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs. Drug Metab Pharmacokinet 23: 223–235.
- 21
- 22, , , ( 2001) Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J Biol Chem 276: 35669–35675.
- 23, , , , , , , , , ( 2007) Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics. Clin Pharmacol Ther 81: 76–82.

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