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Design of a heterotetrameric coiled coil
Article first published online: 2 DEC 2008
DOI: 10.1002/pro.30
Copyright © 2008 The Protein Society
Additional Information
How to Cite
Root, B. C., Pellegrino, L. D., Crawford, E. D., Kokona, B. and Fairman, R. (2009), Design of a heterotetrameric coiled coil. Protein Science, 18: 329–336. doi: 10.1002/pro.30
Publication History
- Issue published online: 30 JAN 2009
- Article first published online: 2 DEC 2008
- Accepted manuscript online: 2 DEC 2008 12:00AM EST
- Manuscript Accepted: 3 NOV 2008
- Manuscript Revised: 25 OCT 2008
- Manuscript Received: 23 JUN 2008
Funded by
- NSF. Grant Numbers: MCB-0211754, MCB-0516025
References
- 1, ( 2005) Peptides as novel smart materials. Curr Opin Struct Biol 15: 453–463.
- 2( 2005) The design of coiled-coil structures and assemblies. Adv Protein Chem 70: 79–112.
- 3, ( 2006) Peptide-based fibrous biomaterials: some things old, new and borrowed. Curr Opin Chem Biol 10: 559–567.
- 4, , , , , ( 1996) Design of heterotetrameric coiled coils: evidence for increased stabilization by Glu(−)-Lys(+) ion pair interactions. Biochemistry 35: 2824–2829.
- 5, ( 1995) A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil. Biochemistry 34: 8642–8648.
- 6, ( 1998) A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil. Biochemistry 37: 13042.
- 7, ( 2001) A designed protein with packing between left-handed and right-handed helices. Biochemistry 40: 8981–8989.
- 8, , , ( 1993) Genetic analysis of the leucine heptad repeats of Lac repressor: evidence for a 4-helical bundle. EMBO J 12: 3227–3236.
- 9, , ( 1994) A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions. EMBO J 13: 2849–2861.
- 10, , , ( 1993) A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science 262: 1401–1407.
- 11, , , ( 2000) De novo design of helical bundles as models for understanding protein folding and function. Acc Chem Res 33: 745–754.
- 12, , ( 1993) Metal ion-dependent modulation of the dynamics of a designed protein. Science 261: 879–885.
- 13, ( 2003) Extended knobs-into-holes packing in classical and complex coiled-coil assemblies. J Struct Biol 144: 349–361.
- 14, , , ( 2001) Effects of charged amino acids at b and c heptad positions on specificity and stability of four-chain coiled coils. Protein Sci 10: 631–637.Direct Link:
- 15, , , , ( 1995) How to measure and predict the molar absorption coefficient of a protein. Protein Sci 4: 2411–2423.Direct Link:
- 16, ( 1998) Deciphering rules of helix stability in peptides. Methods Enzymol 295: 1–26.
- 17, , , , , ( 1997) A protein designed by binary patterning of polar and nonpolar amino acids displays native-like properties. J Am Chem Soc 119: 5302–5306.
- 18, ( 1995) Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper. Science 268: 436–439.
- 19, , , ( 1996) Ion pairs significantly stabilize coiled-coils in the absence of electrolyte. J Mol Biol 255: 367–372.
- 20, , ( 1998) Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids. J Mol Biol 279: 959–972.
- 21, , ( 2000) Interhelical ion pairing in coiled coils: solution structure of a heterodimeric leucine zipper and determination of pKa values of Glu side chains. Biochemistry 39: 12804–12818.
- 22, , , ( 1981) Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. Biophys J 36: 575–588.
- 23, , , , Computer-aided interpretation of analytical sedimentation data for proteins. In: HardingSE, RoweAJ, HortonJC, Eds. ( 1992) Analytical ultracentrifugation in biochemistry and polymer science. Cambridge: The Royal Society of Chemistry. pp 90–125
- 24, , , , , ( 2000) Sticky-end assembly of a designed peptide fiber provides insight into protein fibrillogenesis. Biochemistry 39: 8728–8734.