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Engineering antibody fragments to fold in the absence of disulfide bonds

  1. Min Jeong Seo1,2,
  2. Ki Jun Jeong6,
  3. Clinton E. Leysath2,
  4. Andrew D. Ellington2,3,
  5. Brent L. Iverson2,3,
  6. George Georgiou1,2,4,5,*

Article first published online: 2 DEC 2008

DOI: 10.1002/pro.31

Issue

Protein Science

Protein Science

Volume 18, Issue 2, pages 259–267, February 2009

Additional Information

How to Cite

Seo, M. J., Jeong, K. J., Leysath, C. E., Ellington, A. D., Iverson, B. L. and Georgiou, G. (2009), Engineering antibody fragments to fold in the absence of disulfide bonds. Protein Science, 18: 259–267. doi: 10.1002/pro.31

Author Information

  1. 1

    Department of Chemical Engineering, University of Texas, Austin, TX 78712

  2. 2

    Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712

  3. 3

    Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712

  4. 4

    Section of Molecular Genetics and Microbiology, University of Texas, Austin, TX 78712

  5. 5

    Department of Biomedical Engineering, University of Texas, Austin, TX 78712

  6. 6

    Department of Chemical and Biomolecular Engineering Institute for the Bio Century, KAIST, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea

*Department of Chemical Engineering, Cockrell School of Engineering, The University of Texas at Austin, 1 University Station C0400, Austin, TX 78712

Publication History

  1. Issue published online: 30 JAN 2009
  2. Article first published online: 2 DEC 2008
  3. Accepted manuscript online: 2 DEC 2008 12:00AM EST
  4. Manuscript Accepted: 2 NOV 2008
  5. Manuscript Revised: 29 OCT 2008
  6. Manuscript Received: 5 SEP 2008

Funded by

  • ONR
  • DARPA

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