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Mobile loop mutations in an archaeal inositol monophosphatase: Modulating three-metal ion assisted catalysis and lithium inhibition

  1. Zheng Li1,
  2. Kimberly A. Stieglitz2,
  3. Anthony L. Shrout3,†,
  4. Yang Wei1,
  5. Robert M. Weis3,
  6. Boguslaw Stec4,
  7. Mary F. Roberts1,*

Article first published online: 21 DEC 2009

DOI: 10.1002/pro.315

Issue

Protein Science

Protein Science

Volume 19, Issue 2, pages 309–318, February 2010

Additional Information

How to Cite

Li, Z., Stieglitz, K. A., Shrout, A. L., Wei, Y., Weis, R. M., Stec, B. and Roberts, M. F. (2010), Mobile loop mutations in an archaeal inositol monophosphatase: Modulating three-metal ion assisted catalysis and lithium inhibition. Protein Science, 19: 309–318. doi: 10.1002/pro.315

Author Information

  1. 1

    Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467

  2. 2

    Science, Technology, Engineering, and Mathematics, Roxbury Community College, Boston, Massachusetts 02120

  3. 3

    Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003

  4. 4

    The Burnham Institute for Medical Research, La Jolla, California 92037

  1. †

    P.A. Technologies, LLC, Amherst, Massachusetts

*Department of Chemistry, Boston College, Chestnut Hill, MA 02467

Publication History

  1. Issue published online: 21 JAN 2010
  2. Article first published online: 21 DEC 2009
  3. Accepted manuscript online: 21 DEC 2009 12:00AM EST
  4. Manuscript Accepted: 10 DEC 2009
  5. Manuscript Revised: 20 NOV 2009
  6. Manuscript Received: 23 MAR 2009

Funded by

  • Department of Energy Biosciences. Grant Numbers: DE-FG02-91ER20025, NIGMS-68649

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