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Approaches to efficient production of recombinant angiogenesis inhibitor rhVEGI-192 and characterization of its structure and antiangiogenic function

  1. Xu Chen1,†,
  2. Jueheng Wu2,3,†,
  3. Hanning Liu1,†,
  4. Zhenjian He2,3,
  5. Minghui Gu1,
  6. Ning Wang1,
  7. Jianda Ma1,
  8. Jieping Hu1,
  9. Lei Xia1,
  10. Haipeng He1,
  11. Jie Yuan2,4,
  12. Jun Li2,4,
  13. Luyuan Li5,
  14. Mengfeng Li2,3,*,
  15. Xun Zhu2,3,*

Article first published online: 5 JAN 2010

DOI: 10.1002/pro.323

Issue

Protein Science

Protein Science

Volume 19, Issue 3, pages 449–457, March 2010

Additional Information

How to Cite

Chen, X., Wu, J., Liu, H., He, Z., Gu, M., Wang, N., Ma, J., Hu, J., Xia, L., He, H., Yuan, J., Li, J., Li, L., Li, M. and Zhu, X. (2010), Approaches to efficient production of recombinant angiogenesis inhibitor rhVEGI-192 and characterization of its structure and antiangiogenic function. Protein Science, 19: 449–457. doi: 10.1002/pro.323

Author Information

  1. 1

    Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

  2. 2

    Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China

  3. 3

    Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

  4. 4

    Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

  5. 5

    Department of Microbiology, School of Pharmaceutical Sciences, Nankai University, Tianjin, 300071, China

  1. †

    Xu Chen, Jueheng Wu, and Hanning Liu contributed equally to this work.

*Zhongshan School of Medicine, Sun Yat-sen University, 74 Zhongshan Road II, Guangzhou, Guangdong 510080, China

Publication History

  1. Issue published online: 22 FEB 2010
  2. Article first published online: 5 JAN 2010
  3. Manuscript Accepted: 16 DEC 2009
  4. Manuscript Revised: 14 DEC 2009
  5. Manuscript Received: 1 OCT 2009

Funded by

  • Natural Science Foundation of Guangdong Province. Grant Number: 06201946
  • Department of Science and Technology of Guangzhou Municipality. Grant Number: 2006Z3-E4081
  • Medical Science Foundation of Guangdong Province. Grant Number: A2008155
  • 10th “Challenge Cup” Guangdong Extracurricular Sci-tech Project, 12th “Challenge Cup” China Extracurricular Sci-tech Project
  • Grant from Ministry of Science and Technology of China. Grant Number: (2009CB918901 to L.Y Li)

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