SEARCH

SEARCH BY CITATION

References

  • 1
    Young JA, Collier RJ ( 2007) Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annu Rev Biochem 76: 243265.
  • 2
    Klimpel KR, Molloy SS, Thomas G, Leppla SH ( 1992) Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proc Natl Acad Sci USA 89: 1027710281.
  • 3
    Molloy SS, Bresnahan PA, Leppla SH, Klimpel KR, Thomas G ( 1992) Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem 267: 1639616402.
  • 4
    Ezzell JW Jr, Abshire TG ( 1992) Serum protease cleavage of Bacillus anthracis protective antigen. J Gen Microbiol 138: 543549.
  • 5
    Mogridge J, Cunningham K, Collier RJ ( 2002) Stoichiometry of anthrax toxin complexes. Biochemistry 41: 10791082.
  • 6
    Miller CJ, Elliott JL, Collier RJ ( 1999) Anthrax protective antigen: prepore-to-pore conversion. Biochemistry 38: 1043210441.
  • 7
    Nassi S, Collier RJ, Finkelstein A ( 2002) PA63 channel of anthrax toxin: an extended beta-barrel. Biochemistry 41: 14451450.
  • 8
    Katayama H, Janowiak BE, Brzozowski M, Juryck J, Falke S, Gogol EP, Collier RJ, Fisher MT ( 2008) GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore. Nat Struct Mol Biol 15: 754760.
  • 9
    Blaustein RO, Finkelstein A ( 1990) Diffusion limitation in the block by symmetric tetraalkylammonium ions of anthrax toxin channels in planar phospholipid bilayer membranes. J Gen Physiol 96: 943957.
  • 10
    Krantz BA, Trivedi AD, Cunningham K, Christensen KA, Collier RJ ( 2004) Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin. J Mol Biol 344: 739756.
  • 11
    Zhang S, Finkelstein A, Collier RJ ( 2004a) Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel. Proc Natl Acad Sci USA 101: 1675616761.
  • 12
    Zhang S, Udho E, Wu Z, Collier RJ, Finkelstein A ( 2004b) Protein translocation through anthrax toxin channels formed in planar lipid bilayers. Biophys J 87: 38423849.
  • 13
    Blaustein RO, Koehler TM, Collier RJ, Finkelstein A ( 1989) Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers. Proc Natl Acad Sci USA 86: 22092213.
  • 14
    Krantz BA, Finkelstein A, Collier RJ ( 2006) Protein translocation through the anthrax toxin transmembrane pore is driven by a proton gradient. J Mol Biol 355: 968979.
  • 15
    Krantz BA, Melnyk RA, Zhang S, Juris SJ, Lacy DB, Wu Z, Finkelstein A, Collier RJ ( 2005) A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore. Science 309: 777781.
  • 16
    Melnyk RA, Collier RJ ( 2006) A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation. Proc Natl Acad Sci USA 103: 98029807.
  • 17
    Sellman BR, Nassi S, Collier RJ ( 2001) Point mutations in anthrax protective antigen that block translocation. J Biol Chem 276: 83718376.
  • 18
    Mourez M, Yan M, Lacy DB, Dillon L, Bentsen L, Marpoe A, Maurin C, Hotze E, Wigelsworth D, Pimental RA, Ballard JD, Collier RJ, Tweten RK ( 2003) Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci USA 100: 1380313808.
  • 19
    Sellman BR, Mourez M, Collier RJ ( 2001) Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax. Science 292: 695697.
  • 20
    Singh Y, Khanna H, Chopra AP, Mehra V ( 2001) A dominant negative mutant of Bacillus anthracis protective antigen inhibits anthrax toxin action in vivo. J Biol Chem 276: 2209022094.
  • 21
    Blanke SR, Milne JC, Benson EL, Collier RJ ( 1996) Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen. Proc Natl Acad Sci USA 93: 84378442.
  • 22
    Milne JC, Blanke SR, Hanna PC, Collier RJ ( 1995) Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus. Mol Microbiol 15: 661666.
  • 23
    Milne JC, Furlong D, Hanna PC, Wall JS, Collier RJ ( 1994) Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem 269: 2060720612.
  • 24
    Benson EL, Huynh PD, Finkelstein A, Collier RJ ( 1998) Identification of residues lining the anthrax protective antigen channel. Biochemistry 37: 39413948.
  • 25
    Sun J, Vernier G, Wigelsworth DJ, Collier RJ ( 2007) Insertion of anthrax protective antigen into liposomal membranes: effects of a receptor. J Biol Chem 282: 10591065.
  • 26
    Sun J, Lang AE, Aktories K, Collier RJ ( 2008) Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation. Proc Natl Acad Sci USA 105: 43464351.
  • 27
    Lang AE, Neumeyer T, Sun J, Collier RJ, Benz R, Aktories K ( 2008) Amino acid residues involved in membrane insertion and pore formation of Clostridium botulinum C2 toxin. Biochemistry 47: 84068413.
  • 28
    Neumeyer T, Schiffler B, Maier E, Lang AE, Aktories K, Benz R ( 2008) Clostridium botulinum C2 toxin. Identification of the binding site for chloroquine and related compounds and influence of the binding site on properties of the C2II channel. J Biol Chem 283: 39043914.
  • 29
    Lacy DB, Lin HC, Melnyk RA, Schueler-Furman O, Reither L, Cunningham K, Baker D, Collier RJ ( 2005) A model of anthrax toxin lethal factor bound to protective antigen. Proc Natl Acad Sci USA 102: 1640916414.
  • 30
    Lacy DB, Mourez M, Fouassier A, Collier RJ ( 2002) Mapping the anthrax protective antigen binding site on the lethal and edema factors. J Biol Chem 277: 30063010.
  • 31
    Melnyk RA, Hewitt KM, Lacy DB, Lin HC, Gessner CR, Li S, Woods VLJr, Collier RJ ( 2006) Structural determinants for the binding of anthrax lethal factor to oligomeric protective antigen. J Biol Chem 281: 16301635.
  • 32
    Wigelsworth DJ, Krantz BA, Christensen KA, Lacy DB, Juris SJ, Collier RJ ( 2004) Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen. J Biol Chem 279: 2334923356.
  • 33
    Bernard A, Payton M ( 1995) Fermentation and Growth of Escherichia coli for Optimal Protein Production. In: Current protocols in protein science. Hoboken, NJ: Wiley.
  • 34
    Livnah O, Bayer EA, Wilchek M, Sussman JL ( 1993) The structure of the complex between avidin and the dye, 2-(4′-hydroxyazobenzene) benzoic acid (HABA). FEBS Lett 328: 165168.
  • 35
    Wang ZX, Kumar NR, Srivastava DK ( 1992) A novel spectroscopic titration method for determining the dissociation constant and stoichiometry of protein-ligand complex. Anal Biochem 206: 376381.
  • 36
    Mueller P, Rudin DO ( 1963) Resting and action potentials in experimental bimolecular lipid membranes. J Theor Biol 4: 268280.
  • 37
    Blaustein RO, Lea EJ, Finkelstein A ( 1990) Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Single-channel analysis. J Gen Physiol 96: 921942.