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Engineering a G protein-coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state

  1. Aimée Martin1,
  2. Marjorie Damian1,
  3. Michel Laguerre2,
  4. Joseph Parello3,
  5. Bernard Pucci4,
  6. Laurence Serre5,†,
  7. Sophie Mary1,
  8. Jacky Marie1,
  9. Jean-Louis Banères1,*

Article first published online: 6 JAN 2009

DOI: 10.1002/pro.55

Issue

Protein Science

Protein Science

Volume 18, Issue 4, pages 727–734, April 2009

Additional Information

How to Cite

Martin, A., Damian, M., Laguerre, M., Parello, J., Pucci, B., Serre, L., Mary, S., Marie, J. and Banères, J.-L. (2009), Engineering a G protein-coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state. Protein Science, 18: 727–734. doi: 10.1002/pro.55

Author Information

  1. 1

    Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS Universités Montpellier I et II, Faculté de Pharmacie, 15 Av. Ch. Flahault, BP14491, 34093 Montpellier Cedex 5, France

  2. 2

    Institut Européen de Chimie et Biologie, UMR 5248 CNRS, 2 rue Robert-Escarpit, 33607 Pessac Cedex, France

  3. 3

    Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6600, USA

  4. 4

    Laboratoire de Chimie Bioorganique et des Systèmes Moléculaires Vectoriels, Université d'Avignon et des Pays du Vaucluse, Faculté des Sciences, 33 Rue Louis Pasteur, F-84000 Avignon, France

  5. 5

    Laboratoire des Protéines Membranaires, Institut de Biologie Structurale Jean-Pierre Ebel CEA/CNRS/UJF, 41, rue Jules Horowitz, 38027 Grenoble cedex 01, France

  1. †

    ESRF, Partner for Structural Biology, 6, rue Jules Horowitz, 38042 Grenoble, France

*IBMM, Faculté de Pharmacie Bât. K, 15 Av. Charles Flahault, BP14491, 34093 Montpellier Cedex 5, France

Publication History

  1. Issue published online: 25 MAR 2009
  2. Article first published online: 6 JAN 2009
  3. Accepted manuscript online: 6 JAN 2009 12:00AM EST
  4. Manuscript Accepted: 27 NOV 2008
  5. Manuscript Received: 1 SEP 2008

Funded by

  • Ministère de la Recherche. Grant Number: ANR 06-BLAN-0087
  • l'Association pour la Recherche sur le Cancer (subvention libre n°3159)
  • CNRS

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